Which medications are considered first-line treatment options for posttraumatic stress disorder (PTSD)? Select all that apply.

The first-line treatment options for posttraumatic stress disorder (PTSD) include selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs). Sertraline is an SSRI and is recognized for its effectiveness in treating PTSD, as it helps to alleviate symptoms such as anxiety, intrusive thoughts, and hyperarousal.

Paroxetine, another SSRI, is also considered a first-line treatment for PTSD due to its efficacy in reducing the severity of PTSD symptoms. Fluoxetine, also an SSRI, has been supported in clinical guidelines for treating PTSD as well, helping to manage symptoms effectively.

Duloxetine, an SNRI, is specifically noted for its broad application in treating various anxiety and mood disorders, including PTSD. It works by increasing the levels of serotonin and norepinephrine in the brain, which can help alleviate symptoms.

In summary, the medications recognized for first-line treatment options in PTSD include sertraline, paroxetine, fluoxetine, and duloxetine based on their effectiveness in clinical practice.